HMMMM, well she eats chews em till they are gone. I figured since it is a natural product it was ok. Nylabones do not last, atleast if you follow the recommendation of the company, they say to only let them chew till the ends are worn. That only takes her a little while, and for the price of nylabones thats tough. However, she does do well with the nylabone galileo and the turkey leg tuff chew, but she does not like these NEARLY as much as her hooves. Have not had a problem with her throwing up. She does break of pieces and crunches them down.