Funny as it sounds, yes they can. My husbands and my first dog would not stay out of water. Always either in the bay or in her swimming pool (yes I said her swimming pool). Her pads on her paws would get wrinkled and kind of soft which was not always good because when she would run on gravel or hard dirt she would tear her pads. She loved swimming and trying to catch horseshoe crabs, funny as heck to watch her!