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I believe that an extremely stable, confident dog is very hard to ruin.

A mediocre dog can be ruined easier if put in a less than ideal situation, but with some help should recover.

A weak dog, no matter how much help it is given, usually won't rebound from a bad experience.

It really all depends on the dog. Some can handle much more than others. You could have a super strong dog who lives a crappy life, with shitty owners who neglect and/or abuse, yet that dog still remains stable and happy. You could have another dog who has the best home and owners but yet its a total nut case.

Enviornment does play a role, but its the genetics of the animal that determines how it handles stress in its life and how it recovers (if at all) from a bad experience.
 
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